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Article

Genetic mutations associated with isoniazid resistance in Mycobacterium tuberculosis: a systematic review.

PloS one - 1 Jan 2015

Seifert Marva, Catanzaro Donald, Catanzaro Antonino, Rodwell Timothy C

Abstract excerpt

BACKGROUND: Tuberculosis (TB) incidence and mortality are declining worldwide; however, poor detection of drug-resistant disease threatens to reverse current progress toward global TB control. Multiple, rapid molecular diagnostic tests have recently been developed to detect genetic mutations in Mycobacterium tuberculosis (Mtb) genes known to confer first-line drug resistance. Their utility, though, depends on the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25799046
DOI: 10.1371/journal.pone.0119628
PMCID: PMC4370653

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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