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A Systematic Review of Mutations Associated with Isoniazid Resistance Points to Lower Diagnostic Sensitivity for Common Mutations and Increased Incidence of Uncommon Mutations in Clinical Strains of <i>Mycobacterium tuberculosis</i>

2020-06-03

Abstract excerpt

<h4>ABSTRACT</h4> Molecular testing is rapidly becoming integral to the global tuberculosis (TB) control effort. Uncommon mechanisms of resistance can escape detection by these platforms and lead to the development of Multi-Drug Resistant (MDR) strains. This article is a systematic review of published articles that reported isoniazid (INH) resistance-conferring mutations between September-2013 and December-2019. T...

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Literature Corpus work
e1bcacf4-3709-5896-ab69-875803c2af39
DOI
10.1101/2020.05.30.20118075
Open publication

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A Systematic Review of Mutations Associated with Isoniazid Resistance Points to Lower Diagnostic Sensitivity for Common Mutations and Increased Incidence of Uncommon Mutations in Clinical Strains of <i>Mycobacterium tuberculosis</i>DOI 10.1101/2020.05.30.20118075
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