Article
Mutation profiling for detection of isoniazid resistance in Mycobacterium tuberculosis clinical isolates.
The Journal of antimicrobial chemotherapy - 1 Dec 2015
Jagielski Tomasz, Bakuła Zofia, Roeske Katarzyna, Kamiński Michał, Napiórkowska Agnieszka, Augustynowicz-Kopeć Ewa, Zwolska Zofia, Bielecki Jacek
Abstract excerpt
OBJECTIVES: Progress in the detection of drug-resistant TB has been underpinned by the development and implementation of new, reliable and rapid diagnostic tools. These rely mostly on the detection of specific mutations conferring resistance to anti-TB drugs. The aim of this study was to search for mutations associated with isoniazid resistance among Mycobacterium tuberculosis clinical isolates. METHODS: A...
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