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Article

Detection and characterization of mutations in genes related to isoniazid resistance in Mycobacterium tuberculosis clinical isolates from Iran.

Molecular biology reports - 1 Jul 2022

Bakhtiyariniya Pejman, Khosravi Azar Dokht, Hashemzadeh Mohammad, Savari Mohammad

Abstract excerpt

BACKGROUND: The global rise in drug-resistant Mycobacterium tuberculosis (M.tb), and especially the significant prevalence of isoniazid (INH)-resistance constitute a significant challenge to global health. Therefore, the present study aimed to investigate mutations in prevalent gene loci-involved in INH-resistance phenotype-among M.tb clinical isolates from southwestern Iran. METHODS: Drug susceptibility testing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35366177
DOI: 10.1007/s11033-022-07404-2
PMCID: PMC8976162

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