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Article

Detection of mutations associated with isoniazid resistance in Mycobacterium tuberculosis isolates from China.

Journal of clinical microbiology - 1 Nov 2005

Zhang Min, Yue Jun, Yang Yan-Ping, Zhang Hong-Mei, Lei Jian-Qiang, Jin Rui-Liang, Zhang Xue-Lian, Wang Hong-Hai

Abstract excerpt

Nine structural genes (furA, katG, inhA, kasA, Rv0340, iniB, iniA, iniC, and efpA) and two regulatory regions (the oxyR-ahpC intergenic region and the promoter of mabA-inhA) in 87 isoniazid (INH)-monoresistant and 50 INH-susceptible Mycobacterium tuberculosis isolates collected from five provinces of China were analyzed by sequencing. Eighty-two (94.3%) INH-resistant isolates had mutations in the katG gene, with...

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Identifiers

PMID: 16272473
DOI: 10.1128/JCM.43.11.5477-5482.2005
PMCID: PMC1287806

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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