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Article

Effector CD8+ T cells are generated in response to an immunodominant epitope in type III effector YopE during primary Yersinia pseudotuberculosis infection.

Infection and immunity - 1 Jul 2014

Zhang Yue, Mena Patricio, Romanov Galina, Bliska James B

Abstract excerpt

YopE is a virulence factor that is secreted into host cells infected by Yersinia species. The YopE C-terminal domain has GTPase-activating protein (GAP) activity. The YopE N-terminal domain contains an epitope that is an immunodominant CD8(+) T cell antigen during primary infection of C57BL/6 mice with Yersinia pseudotuberculosis. The characteristics of the CD8(+) T cells generated in response to the epitope,...

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Share to Amino Acid Sequence
Share to Bacterial Outer Membrane Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CD8-Positive T-Lymphocytes

Share to Gene Expression Regulation, Bacterial

Share to Immunodominant Epitopes

Share to Virulence

Share to Yersinia Infections

Share to Yersinia pseudotuberculosis

Source

Open in PubMed Open full text

Identifiers

PMID: 24799630
DOI: 10.1128/IAI.01687-14
PMCID: PMC4097610

Genes

TNF
KLRG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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