Article

Heightened virulence of <i>Yersinia</i> is associated with decreased function of the YopJ protein

2021-03-22

Abstract excerpt

Despite the maintenance of YopP/J alleles throughout the human-pathogenic Yersinia lineage, the benefit of YopP/J-induced phagocyte death for Yersinia pathogenesis in animals is not obvious. To determine how sequence divergence of YopP/J has impacted Yersinia virulence, we examined protein polymorphisms in this Type III secreted effector protein across 17 Yersinia species, and tested the consequences of polymo...

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Literature Corpus work: 6d1aef2d-0d0d-552f-88cc-74ca3b0c5da2
DOI: 10.1101/2021.03.22.436461

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