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Article

Heightened Virulence of Yersinia Is Associated with Decreased Function of the YopJ Protein.

Infection and immunity - 16 Nov 2021

Mares Chris A, Lugo Fernando P, Albataineh Mohammad, Goins Beth A, Newton Irene G, Isberg Ralph R, Bergman Molly A

Abstract excerpt

Despite the maintenance of YopP/J alleles throughout the human-pathogenic Yersinia lineage, the benefit of YopP/J-induced phagocyte death for Yersinia pathogenesis in animals is not obvious. To determine how the sequence divergence of YopP/J has impacted Yersinia virulence, we examined protein polymorphisms in this type III secreted effector protein across 17 Yersinia species and tested the consequences of...

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Identifiers

PMID: 34543120
DOI: 10.1128/IAI.00430-21
PMCID: PMC8594599

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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