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Article

Yersinia pseudotuberculosis YopD mutants that genetically separate effector protein translocation from host membrane disruption.

Molecular microbiology - 1 May 2015

Adams Walter, Morgan Jessica, Kwuan Laura, Auerbuch Victoria

Abstract excerpt

The Yersinia type III secretion system (T3SS) translocates Yop effector proteins into host cells to manipulate immune defenses such as phagocytosis and reactive oxygen species (ROS) production. The T3SS translocator proteins YopB and YopD form pores in host membranes, facilitating Yop translocation. While the YopD amino and carboxy termini participate in pore formation, the role of the YopD central region between...

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PMID: 25684661
DOI: 10.1111/mmi.12970

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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