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Article

Yersinia YopE is targeted for type III secretion by N-terminal, not mRNA, signals.

Molecular microbiology - 1 Jan 2001

Lloyd S A, Norman M, Rosqvist R, Wolf-Watz H

Abstract excerpt

Pathogenic Yersinia species inject virulence proteins, known as Yops, into the cytosol of eukaryotic cells. The injection of Yops is mediated via a type III secretion system. Previous studies have suggested that YopE is targeted for secretion by two signals. One is mediated by its cognate chaperone YerA, whereas the other consists of either the 5' end of yopE mRNA or the N-terminus of YopE. In order to...

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PMID: 11136471
DOI: 10.1046/j.1365-2958.2001.02271.x

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