Article
Impact of CCR7 on T-Cell Response and Susceptibility to Yersinia pseudotuberculosis Infection.
The Journal of infectious diseases - 15 Sept 2017
Pezoldt Joern, Pisano Fabio, Heine Wiebke, Pasztoi Maria, Rosenheinrich Maik, Nuss Aaron M, Pils Marina C, Prinz Immo, Förster Reinhold, Huehn Jochen, Dersch Petra
Abstract excerpt
Background: To successfully limit pathogen dissemination, an immunological link between the entry tissue of the pathogen and the underlying secondary lymphoid organs (SLOs) needs to be established to prime adaptive immune responses. Here, the prerequisite of CCR7 to mount host immune responses within SLOs during gastrointestinal Yersinia pseudotuberculosis infection to limit pathogen spread was investigated....
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