Article
The contribution of viral genotype to plasma viral set-point in HIV infection.
PLoS pathogens - 1 May 2014
Hodcroft Emma, Hadfield Jarrod D, Fearnhill Esther, Phillips Andrew, Dunn David, O'Shea Siobhan, Pillay Deenan, Leigh Brown Andrew J
Abstract excerpt
Disease progression in HIV-infected individuals varies greatly, and while the environmental and host factors influencing this variation have been widely investigated, the viral contribution to variation in set-point viral load, a predictor of disease progression, is less clear. Previous studies, using transmission-pairs and analysis of phylogenetic signal in small numbers of individuals, have produced a wide...
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