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Article

Cumulative Impact of Host and Viral Factors on HIV-1 Viral-Load Control during Early Infection

31 Oct 2012

Abstract excerpt

In HIV-1 infection, the early set-point viral load strongly predicts both viral transmission and disease progression. The factors responsible for the wide spectrum of set-point viral loads are complex and likely reflect an interplay between the transmitted virus and genetically defined factors in both the transmitting source partner and the seroconverter. Indeed, analysis of 195 transmission pairs from Lusaka,...

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PMID: 23115285
DOI: 10.1128/jvi.02118-12

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