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Genetic analysis reveals the complex structure of HIV-1 transmission within defined risk groups

14 Mar 2005

Abstract excerpt

We explored the epidemic history of HIV-1 subtype B in the United Kingdom by using statistical methods that infer the population history of pathogens from sampled gene sequence data. Phylogenetic analysis of HIV-1 pol gene sequences from Britain showed at least six large transmission chains, indicating a genetically variable, but epidemiologically homogeneous, epidemic among men having sex with men. Through...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 15767575
DOI: 10.1073/pnas.0407534102

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