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Article

High Heritability Is Compatible with the Broad Distribution of Set Point Viral Load in HIV Carriers

6 Feb 2015

Abstract excerpt

Set point viral load in HIV patients ranges over several orders of magnitude and is a key determinant of disease progression in HIV. A number of recent studies have reported high heritability of set point viral load implying that viral genetic factors contribute substantially to the overall variation in viral load. The high heritability is surprising given the diversity of host factors associated with controlling...

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PMID: 25658741
DOI: 10.1371/journal.ppat.1004634

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