Article

A phylogeny-aware GWAS framework to correct for heritable pathogen effects on infectious disease traits

2021-12-02

Abstract excerpt

Infectious diseases are a unique challenge for genome-wide association studies (GWAS) because pathogen, host, and environmental factors can all affect disease traits. Previous GWAS have successfully identified several human genetic variants associated with HIV-1 set point viral load (spVL), among other important infectious disease traits. However, these GWAS do not account for potentially confounding or extraneous...

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Literature Corpus work: fe61c7d3-ce42-5d01-a5f4-13bc5190a113
DOI: 10.1101/2021.11.22.21266687

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