Article

Estimating the respective contributions of human and viral genetic variation to HIV control

2015-10-14

Abstract excerpt

We evaluated the fraction of variation in HIV-1 set point viral load attributable to viral or human genetic factors by using joint host/pathogen genetic data from 541 HIV infected individuals. We show that viral genetic diversity explains 29% of the variation in viral load while host factors explain 8.4%. Using a joint model including both host and viral effects, we estimate a total of 30% heritability, indicating...

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Literature Corpus work: 57e3b880-e155-5802-84f3-e07696ea6eed
DOI: 10.1101/029017

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