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Article

Rapid and sensitive intraoperative detection of mutations in the isocitrate dehydrogenase 1 and 2 genes during surgery for glioma.

Journal of neurosurgery - 1 Jun 2014

Kanamori Masayuki, Kikuchi Atsuo, Watanabe Mika, Shibahara Ichiyo, Saito Ryuta, Yamashita Yoji, Sonoda Yukihiko, Kumabe Toshihiro, Kure Shigeo, Tominaga Teiji

Abstract excerpt

OBJECT: Intraoperative diagnosis is important in determining the strategies during surgery for glioma. Because the mutations in the isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) genes have diagnostic, prognostic, and predictive values, the authors assessed the feasibility and significance of a...

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Source

Identifiers

PMID: 24745708
DOI: 10.3171/2014.3.JNS131505

Genes

IDH1
IDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24745708-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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