Article

Rapid Perioperative IDH1 Mutation Detection in High-Grade Gliomas using Novel LAMP assay

2023-08-11

Abstract excerpt

<title>Abstract</title> <p><bold>Introduction:</bold> Molecular subtyping is integral in the classification of gliomas and increasingly guides the oncologic and neurosurgical management of these tumors. In high-grade gliomas, the presence or absence of the isocitrate dehydrogenase-1 (IDH1) mutation has major prognostic and diagnostic implications for surgical and therapeutic decision-making. The wait time for mol...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 27f8e106-7a33-512d-8ec9-02af52868529
DOI: 10.21203/rs.3.rs-3207603/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Rapid Perioperative IDH1 Mutation Detection in High-Grade Gliomas using Novel LAMP assayDOI 10.21203/rs.3.rs-3207603/v1Read

Rapid extraction-free detection of the R132H isocitrate dehydrogenase mutation in glioma using colorimetric peptide nucleic acid-loop mediated isothermal amplification (CPNA-LAMP).Semantic proximity Read

Ultra-early stage lower-grade gliomas: How can we define and differentiate these easily misdiagnosed gliomas through intraoperative molecular diagnosis.Semantic proximity Read

Microfluidics for rapid detection of isocitrate dehydrogenase 1 mutation for intraoperative application.Semantic proximity Read

Clinical utility of a blood based assay for the detection of IDH1.R132H-mutant gliomas.Semantic proximity Read

Qualitative and Quantitative Analysis of IDH1 Mutation in Progressive Gliomas by Allele-Specific qPCR and Western Blot AnalysisSemantic proximity Read

Rapid intraoperative genetic analysis of adult-type diffuse gliomas using a microfluidic real-time polymerase chain reaction device.Semantic proximity Read

Development of a Rapid and Sensitive IDH1/2 Mutation Detection Method for Glial Tumors and a Comparative Mutation Analysis of 236 Glial Tumor Samples.Semantic proximity Read

A new sensitive PCR assay for one-step detection of 12 IDH1/2 mutations in glioma.Semantic proximity Read

A novel high-sensitivity assay to detect a small fraction of mutant IDH1 using droplet digital PCR.Semantic proximity Read

Evaluation of the rapid Idylla IDH1-2 mutation assay in FFPE glioma samples.Semantic proximity Read

Clinical Evaluation of IDH Mutation Status in Formalin-Fixed Paraffin-Embedded Tissue in Gliomas.Semantic proximity Read

Application of Intraoperative Rapid Molecular Diagnosis in Precision Surgery for Glioma: Mimic the World Health Organization CNS5 Integrated Diagnosis.Semantic proximity Read