Article
A surgical strategy for lower grade gliomas using intraoperative molecular diagnosis.
Brain tumor pathology - 1 Jul 2018
Koriyama Shunichi, Nitta Masayuki, Kobayashi Tatsuya, Muragaki Yoshihiro, Suzuki Akane, Maruyama Takashi, Komori Takashi, Masui Kenta, Saito Taiichi, Yasuda Takayuki, Hosono Junji, Okamoto Saori, Shioyama Takahiro, Yamatani Hiroaki, Kawamata Takakazu
Abstract excerpt
Lower grade gliomas are both treated and diagnosed via surgical resection. Maximum tumor resection is currently the standard of care; however, this risks the loss of brain function. Glioma can be genetically subdivided into three different types, based on isocitrate dehydrogenase (IDH) mutation status and the presence of 1p/19q codeletion, which have radically different prognoses and responses to adjuvant...
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