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Article

Ultra-early stage lower-grade gliomas: How can we define and differentiate these easily misdiagnosed gliomas through intraoperative molecular diagnosis.

CNS neuroscience & therapeutics - 1 Oct 2024

Han Zhe, Wang Qingtong, Li Jia, Chi Huizhong, Ma Caizhi, Jia Deze, Qi Mei, Li Xueen, Zhang Kailiang, Feng Zichao, Xue Hao, Li Gang

Abstract excerpt

BACKGROUND: Some lower-grade gliomas (LGG) are difficult to distinguish morphologically from glial cell proliferation or inflammatory changes during surgery, leading to a high risk of incorrect diagnosis. It is crucial to differentiate between the two for making surgical decisions. We define these critical cases as "ultra early stage lower-grade gliomas (UES-LGG)". METHODS: We analyzed 11 out of 13 cases...

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PMID: 39385311
DOI: 10.1111/cns.70044
PMCID: PMC11464210

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