Article
Method for the Intraoperative Detection of IDH Mutation in Gliomas with Differential Mobility Spectrometry.
Current oncology (Toronto, Ont.) - 4 May 2022
Haapala Ilkka, Kondratev Anton, Roine Antti, Mäkelä Meri, Kontunen Anton, Karjalainen Markus, Laakso Aki, Koroknay-Pál Päivi, Nordfors Kristiina, Haapasalo Hannu, Oksala Niku, Vehkaoja Antti, Haapasalo Joonas
Abstract excerpt
Isocitrate dehydrogenase (IDH) mutation status is an important factor for surgical decision-making: patients with IDH-mutated tumors are more likely to have a good long-term prognosis, and thus favor aggressive resection with more survival benefit to gain. Patients with IDH wild-type tumors have generally poorer prognosis and, therefore, conservative resection to avoid neurological deficit is favored. Current...
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