Article
Genetic variants of microRNA sequences and susceptibility to sepsis in patients with major blunt trauma.
Annals of surgery - 1 Jan 2015
Zhang An-qiang, Gu Wei, Zeng Ling, Zhang Lian-yang, Du Ding-yuan, Zhang Mao, Hao Jiang, Yue Cai-li, Jiang Jianxin
Abstract excerpt
OBJECTIVE: The objective of this study was to conduct a systematic survey of common precursor microRNA (pre-miRNA) single nucleotide polymorphisms (SNPs) and evaluate their clinical relevance in patients with major blunt trauma. BACKGROUND: Recent evidence indicates that small noncoding RNA molecules known as miRNAs can function as important negative gene regulators and are implicated in the pathogenesis of...
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