Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Melanocortin-1 Receptor Polymorphisms and the Risk of Complicated Sepsis After Trauma: A Candidate Gene Association Study.

Shock (Augusta, Ga.) - 1 Jan 2017

Seaton Max E, Parent Brodie A, Sood Ravi F, Wurfel Mark M, Muffley Lara A, O'Keefe Grant E, Gibran Nicole S

Abstract excerpt

OBJECTIVE: The aim of the study was to determine if melanocortin-1 receptor (MC1R) single nucleotide polymorphisms (SNPs) are associated with complicated sepsis after trauma. BACKGROUND: Nosocomial infections are an important cause of morbidity and mortality after trauma. Several SNPs in inflammation-related genes have been associated with sepsis. MC1R is an anti-inflammatory mediator that may be involved in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cross Infection
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

Share to Principal Component Analysis

Share to Receptor, Melanocortin, Type 1

Share to Sepsis

Share to Wounds and Injuries

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 27488084
DOI: 10.1097/SHK.0000000000000708
PMCID: PMC5167637

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Melanocortin-1 Receptor Polymorphisms and the Risk of Complicated Sepsis After Trauma: A Candidate Gene Association Study.PMID 27488084Read ↗

Toll-like receptor 1 polymorphisms and associated outcomes in sepsis after traumatic injury: a candidate gene association study.Semantic proximity Read ↗

Variation in the TLR4 gene influences the risk of organ failure and shock posttrauma: a cohort study.Semantic proximity Read ↗

Polymorphisms in the toll-like receptor 9 gene associated with sepsis and multiple organ dysfunction after major blunt trauma.Semantic proximity Read ↗

Single-nucleotide polymorphisms in the Toll-like receptor pathway increase susceptibility to infections in severely injured trauma patients.Semantic proximity Read ↗

Effects of Sequence Variations in Innate Immune Response Genes on Infectious Outcome in Trauma Patients: A Comprehensive Review.Semantic proximity Read ↗

Clinical relevance of single nucleotide polymorphisms within the entire NLRP3 gene in patients with major blunt trauma.Semantic proximity Read ↗

Sepsis syndrome and death in trauma patients are associated with variation in the gene encoding tumor necrosis factor.Semantic proximity Read ↗

Toll-like receptor 1 polymorphisms affect innate immune responses and outcomes in sepsis.Semantic proximity Read ↗

Genetic variants of microRNA sequences and susceptibility to sepsis in patients with major blunt trauma.Semantic proximity Read ↗

TLR4 and TNF-alpha polymorphisms are associated with an increased risk for severe sepsis following burn injury.Semantic proximity Read ↗

Clinical relevance of the TLR4 11367 polymorphism in patients with major trauma.Semantic proximity Read ↗

Genetic predisposition for development of complications in multiple trauma patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.