Article
YY1 acts as a transcriptional activator of Hoxa5 gene expression in mouse organogenesis.
PloS one - 1 Jan 2014
Bérubé-Simard Félix-Antoine, Prudhomme Christelle, Jeannotte Lucie
Abstract excerpt
The Hox gene family encodes homeodomain-containing transcriptional regulators that confer positional information to axial and paraxial tissues in the developing embryo. The dynamic Hox gene expression pattern requires mechanisms that differentially control Hox transcription in a precise spatio-temporal fashion. This implies an integrated regulation of neighbouring Hox genes achieved through the sharing and the...
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