Specification of axial identity in the mouse: role of the Hoxa-5 (Hox1.3) gene.

doi:10.1101/gad.7.11.2085

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Article

Specification of axial identity in the mouse: role of the Hoxa-5 (Hox1.3) gene.

Genes & development - 1 Nov 1993

Jeannotte L, Lemieux M, Charron J, Poirier F, Robertson E J

Abstract excerpt

Numerous lines of study have suggested that the Hox genes, encoding putative transcription factors, are key genes in the establishment of the body plan of the mammalian embryo. To examine the role of Hoxa-5 (Hox1.3) gene during development, we have used targeted mutagenesis in embryonic stem cell...

Topics

Animals
Blastocyst
Blotting, Southern
Bone Development
Bone and Bones
DNA
DNA-Binding Proteins
Genes, Homeobox
Genes, Lethal
Genotype
Homeodomain Proteins
Homozygote
Mice
Mice, Inbred C57BL
Mice, Inbred Strains
Mice, Transgenic
Phosphoproteins
Transcription Factors

Source

Open in PubMed

Identifiers

PMID: 7901120
DOI: 10.1101/gad.7.11.2085

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7901120-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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