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Article

Specification of axial identity in the mouse: role of the Hoxa-5 (Hox1.3) gene.

Genes & development - 1 Nov 1993

Jeannotte L, Lemieux M, Charron J, Poirier F, Robertson E J

Abstract excerpt

Numerous lines of study have suggested that the Hox genes, encoding putative transcription factors, are key genes in the establishment of the body plan of the mammalian embryo. To examine the role of Hoxa-5 (Hox1.3) gene during development, we have used targeted mutagenesis in embryonic stem cells to produce a strain of mice carrying a disrupted Hoxa-5 allele. The viability of homozygous mutant mice is markedly...

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PMID: 7901120
DOI: 10.1101/gad.7.11.2085

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Specification of axial identity in the mouse: role of the Hoxa-5 (Hox1.3) gene.PMID 7901120Read ↗

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