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Article

YY1 is a transcriptional activator of mouse LINE-1 Tf subfamily

2024-01-04

Abstract excerpt

Long interspersed element type 1 (LINE-1, L1) is an active autonomous transposable element (TE) in the human genome. The first step of L1 replication is transcription, which is controlled by an internal RNA polymerase II promoter in the 5’ untranslated region (UTR) of a full-length L1. It has been shown that transcription factor YY1 binds to a conserved sequence motif at the 5’ end of the human L1 5’UTR and dictat...

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Identifiers and source

Literature Corpus work
86cfb79c-3d4e-51eb-a1bb-e5257c61d18a
DOI
10.1101/2024.01.03.573552
Open publication

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YY1 is a transcriptional activator of mouse LINE-1 Tf subfamilyDOI 10.1101/2024.01.03.573552
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