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Article

Impact of the loss of Hoxa5 function on lung alveogenesis.

The American journal of pathology - 1 Oct 2006

Mandeville Isabel, Aubin Josée, LeBlanc Michelle, Lalancette-Hébert Mélanie, Janelle Marie-France, Tremblay Guy M, Jeannotte Lucie

Abstract excerpt

The involvement of genes controlling embryonic processes in the etiology of diseases often escapes attention because of the focus given to their inherent developmental role. Hoxa5 belongs to the Hox gene family encoding transcription factors known for their role in skeletal patterning. Hoxa5 is required for embryonic respiratory tract morphogenesis. We now show that the loss of Hoxa5 function has severe...

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Identifiers

PMID: 17003488
DOI: 10.2353/ajpath.2006.051333
PMCID: PMC1698857

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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