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Article

Peroxisome proliferator-activated receptor γ-mediated induction of microRNA-145 opposes tumor phenotype in colorectal cancer.

Biochimica et biophysica acta - 1 Jun 2014

Panza Anna, Votino Carolina, Gentile Annamaria, Valvano Maria Rosaria, Colangelo Tommaso, Pancione Massimo, Micale Lucia, Merla Giuseppe, Andriulli Angelo, Sabatino Lina, Vinciguerra Manlio, Prattichizzo Clelia, Mazzoccoli Gianluigi, Colantuoni Vittorio, Piepoli Ada

Abstract excerpt

UNLABELLED: MicroRNAs (miRNAs) regulate diverse biological processes by inhibiting translation or inducing degradation of target mRNAs. miR-145 is a candidate tumor suppressor in colorectal carcinoma (CRC). Colorectal carcinogenesis involves deregulation of cellular processes controlled by a number of intertwined chief transcription factors, such as PPARγ and SOX9. Since PPAR family members are able to modulate...

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PMID: 24631504
DOI: 10.1016/j.bbamcr.2014.03.003

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SOX9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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