Article
MicroRNA miR-145 inhibits proliferation, invasiveness, and stem cell phenotype of an in vitro endometriosis model by targeting multiple cytoskeletal elements and pluripotency factors.
Fertility and sterility - 1 Apr 2013
Adammek Marlene, Greve Burkhard, Kässens Nadja, Schneider Cornelia, Brüggemann Kathrin, Schüring Andreas N, Starzinski-Powitz Anna, Kiesel Ludwig, Götte Martin
Abstract excerpt
OBJECTIVE: To study the function of miR-145, known to be dysregulated in endometriosis, and to identify its target genes in an in vitro endometriosis model. DESIGN: Experimental laboratory study. SETTING: University medical centers. PATIENT(S): Primary endometrial stroma cells were derived from eutopic endometrium of three American Society for Reproductive Medicine stage III endometriosis patients and from...
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