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Article

MicroRNA-145 Targets YES and STAT1 in Colon Cancer Cells

20 Jan 2010

Abstract excerpt

BACKGROUND: MicroRNAs (miRNAs) have emerged as important gene regulators and are recognized as key players in tumorigenesis. miR-145 is reported to be down-regulated in several cancers, but knowledge of its targets in colon cancer remains limited. METHODOLOGY/PRINCIPAL FINDINGS: To investigate the role of miR-145 in colon cancer, we have employed a microarray based approach to identify miR-145 targets. Based on...

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PMID: 20098684
DOI: 10.1371/journal.pone.0008836

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