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Article

MiR‐145 inhibits human colorectal cancer cell migration and invasion via PAK4‐dependent pathway

24 Apr 2017

Abstract excerpt

MicroRNA-145 (miR-145), as a tumor-suppressive miRNA, has been demonstrated down-regulated in colorectal cancer (CRC) cells, and could inhibit CRC cells growth. However, the molecular pathway in which miR-145 modulates CRC malignant transformation has not been fully revealed. Here, we reported an intense correlation between the expressions of PAK4 and miR-145 in human CRC cell lines. Transwell assay verified...

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PMID: 28440035
DOI: 10.1002/cam4.1029

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