Article
TLR4 gene polymorphism in patients with nonalcoholic fatty liver disease in comparison to healthy controls.
Metabolic syndrome and related disorders - 1 Apr 2014
Kiziltas Safak, Ata Pinar, Colak Yasar, Mesçi Banu, Senates Ebubekir, Enc Feruze, Ulasoglu Celal, Tuncer Ilyas, Oguz Aytekin
Abstract excerpt
OBJECTIVES: Recent studies have suggested that bacterial overgrowth and endotoxemia along with its receptor, Toll-like receptor 4 (TLR-4), play a role in the pathogenesis of nonalcoholic fatty liver disease (NAFLD). The present study was designed to test and evaluate the TLR4 gene polymorphism in patients with NAFLD in comparison to healthy controls. METHODS: A total of 119 patients [mean (standard deviation, SD)...
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