Article
Lack of Association between Polymorphisms of the TLR4 Gene and Infection with the Hepatitis B and C Viruses.
Mediators of inflammation - 1 Jan 2015
Pires-Neto Orlando de Souza, de Sá Keyla Santos Guedes, Santana Barbara Brasil, Gomes Samara Tatielle Monteiro, Amoras Ednelza da Silva Graça, Conde Simone Regina da Silva, Demachki Sâmia, Azevedo Vânia Nakauth, Martins-Feitosa Rosimar Neris, Ishak Marluísa de Oliveira Guimarães, Ishak Ricardo, Vallinoto Antonio Carlos Rosário
Abstract excerpt
Toll-like receptor 4 (TLR4) plays a crucial role in the early recognition of pathogenic microorganisms and provides an ideal model to investigate the consequences of genetic variation and susceptibility to diseases. The present study investigated the occurrence of the single nucleotide polymorphisms (SNPs) rs4986790 (A>G) and rs4986791 (C>T) in the TLR4 gene in chronic carriers of the hepatitis B (HBV) and C...
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