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Article

Toll-like receptor 4 D299G polymorphism in metabolic disorders: a meta-analysis.

Molecular biology reports - 1 Apr 2013

Belforte F S, Coluccio Leskow F, Poskus E, Penas Steinhardt A

Abstract excerpt

The toll-like receptor 4 (TLR4) plays a key role in the activation of innate immune response participating in the recognition of lipopolysaccharides. Changes in the innate immune response are involved in the pathogenesis of some metabolic disorders such as metabolic syndrome and type 2 diabetes mellitus (Met-S and T2DM). It has been recently shown the role of gut microbiota in the perpetuation of both insulin...

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Source

Identifiers

PMID: 23275193
DOI: 10.1007/s11033-012-2374-5

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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