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Article

Single Nucleotide Polymorphisms of Toll-like Receptor 4 in Hepatocellular Carcinoma-A Single-Center Study.

International journal of molecular sciences - 21 Aug 2022

Androutsakos Theodoros, Bakasis Athanasios-Dimitrios, Pouliakis Abraham, Gazouli Maria, Vallilas Christos, Hatzis Gregorios

Abstract excerpt

Hepatocellular carcinoma (HCC) is the most common primary liver tumor leading to significant morbidity and mortality; its exact genetic background is largely unrecognized. Toll-like receptor-4 (TLR4) reacts with lipopolysaccharides, molecules found in the outer membrane of Gram-negative bacteria. In damaged liver, TLR4 expression is upregulated, leading to hepatic inflammation and injury. We tried to investigate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Liver Cirrhosis

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Source

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Identifiers

PMID: 36012696
DOI: 10.3390/ijms23169430
PMCID: PMC9409058

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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