Article
Genetic polymorphism in CD14 gene, a co-receptor of TLR4 associated with non-alcoholic fatty liver disease.
World journal of gastroenterology - 14 Nov 2016
Kapil Shweta, Duseja Ajay, Sharma Bal Krishan, Singla Bhupesh, Chakraborti Anuradha, Das Ashim, Ray Pallab, Dhiman Radha K, Chawla Yogesh
Abstract excerpt
AIM: To evaluate the pathogenic role of toll-like receptor (TLR) gene polymorphisms in patients with non-alcoholic fatty liver disease (NAFLD). METHODS: Two hundred and fifty subjects (NAFLD = 200, healthy volunteers = 50) underwent polymerase chain reaction and restriction fragment length polymorphism to assess one polymorphism in the toll-like receptor 2 (TLR2) gene (A753G), two polymorphisms in the TLR4 gene...
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