Article
TLR4 polymorphism and haplotype are associated with obesity and lipid profile in young population: a pilot study.
Journal of endocrinological investigation - 1 May 2023
Rodríguez-García R, Vazquez-Villamar M, Aparicio-Ozores G, Parra-Rojas I, Radilla-Vázquez R B, Castro-Alarcón N
Abstract excerpt
BACKGROUND: The single nucleotide polymorphisms in the TLR4 gene can decrease or increase the response to lipopolysaccharide, increasing the susceptibility to inflammatory diseases, affecting the expression or receptor function by inducing a low-grade chronic inflammatory response. PURPOSE: The objective of this study was to evaluate the association of SNPs - 2570 A > G (rs2737190), - 2081 G > A (rs10983755), 896...
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