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Article

TLR4 Receptor D299G/T399I Haplotype Polymorphism Is Associated with Insulin Resistance in Obese Female Subjects.

Genes - 17 Jul 2020

Sharif Elham, Al-Wakeel Mariam, Mohamed Afnan, Kerkadi Abdelhamid, Rizk Nasser

Abstract excerpt

BACKGROUND: Activation of Toll-like-receptor 4 (TLR4) causes chronic inflammation that can result in obesity and metabolic syndrome (MeS). AIM: This study aimed to investigate the role of TLR4 polymorphisms of TLR4D299G/T399I, and its impact on protein expression of TLR4 in obese female subjects. METHODOLOGY: A prospective cross-sectional association study was performed on Arab female subjects from Qatar...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32708841
DOI: 10.3390/genes11070814
PMCID: PMC7397302

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