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Article

Loss of Caenorhabditis elegans BRCA1 promotes genome stability during replication in smc-5 mutants.

Genetics - 1 Apr 2014

Wolters Stefanie, Ermolaeva Maria A, Bickel Jeremy S, Fingerhut Jaclyn M, Khanikar Jayshree, Chan Raymond C, Schumacher Björn

Abstract excerpt

DNA damage by ultraviolet (UV) light poses a risk for mutagenesis and a potential hindrance for cell cycle progression. Cells cope with UV-induced DNA damage through two general strategies to repair the damaged nucleotides and to promote cell cycle progression in the presence of UV-damaged DNA. Defining the genetic pathways and understanding how they function together to enable effective tolerance to UV remains...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24424777
DOI: 10.1534/genetics.113.158295
PMCID: PMC3982690

Genes

BRCA1
BARD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Loss of Caenorhabditis elegans BRCA1 promotes genome stability during replication in smc-5 mutants.PMID 24424777Read ↗

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