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Article

Structural maintenance of chromosomes (SMC) proteins promote homolog-independent recombination repair in meiosis crucial for germ cell genomic stability.

PLoS genetics - 22 Jul 2010

Bickel Jeremy S, Chen Liting, Hayward Jin, Yeap Szu Ling, Alkers Ashley E, Chan Raymond C

Abstract excerpt

In meiosis, programmed DNA breaks repaired by homologous recombination (HR) can be processed into inter-homolog crossovers that promote the accurate segregation of chromosomes. In general, more programmed DNA double-strand breaks (DSBs) are formed than the number of inter-homolog crossovers, and the excess DSBs must be repaired to maintain genomic stability. Sister-chromatid (inter-sister) recombination is...

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Identifiers

PMID: 20661436
DOI: 10.1371/journal.pgen.1001028
PMCID: PMC2908675

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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