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Novel insights into RAD51 activity and regulation during homologous recombination and DNA replication

31 Mar 2016

Abstract excerpt

In this review we focus on new insights that challenge our understanding of homologous recombination (HR) and Rad51 regulation. Recent advances using high-resolution microscopy and single molecule techniques have broadened our knowledge of Rad51 filament formation and strand invasion at double-strand break (DSB) sites and at replication forks, which are one of most physiologically relevant forms of HR from yeast...

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PMID: 27224545
DOI: 10.1139/bcb-2016-0012

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