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Article

Micronucleus frequency in copper-mine workers exposed to arsenic is modulated by the AS3MT Met287Thr polymorphism.

Mutation research. Genetic toxicology and environmental mutagenesis - 1 Jan 2014

Hernández Alba, Paiva Leiliane, Creus Amadeu, Quinteros Domingo, Marcos Ricard

Abstract excerpt

Arsenic(III)methyltransferase (AS3MT) has been demonstrated to be the key enzyme in the metabolism of arsenic as it catalyses the methylation of arsenite and monomethylarsonic acid (MMA) to form methylated arsenic species, which have higher toxic and genotoxic potential than the parent compounds. The aim of this study is to evaluate if genetic variation in the AS3MT gene influences arsenic-induced cytogenetic...

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Identifiers

PMID: 24361376
DOI: 10.1016/j.mrgentox.2013.09.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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