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Article

Genetic variation in arsenic (+3 oxidation state) methyltransferase (AS3MT), arsenic metabolism and risk of basal cell carcinoma in a European population.

Environmental and molecular mutagenesis - 1 Jan 2015

Engström Karin S, Vahter Marie, Fletcher Tony, Leonardi Giovanni, Goessler Walter, Gurzau Eugen, Koppova Kvetoslava, Rudnai Peter, Kumar Rajiv, Broberg Karin

Abstract excerpt

Exposure to inorganic arsenic increases the risk of basal cell carcinoma (BCC). Arsenic metabolism is a susceptibility factor for arsenic toxicity, and specific haplotypes in arsenic (+3 oxidation state) methyltransferase (AS3MT) have been associated with increased urinary fractions of the most toxic arsenic metabolite, methylarsonic acid (MMA). The aim of this study is to elucidate the association of AS3MT...

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Identifiers

PMID: 25156000
DOI: 10.1002/em.21896
PMCID: PMC4322484

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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