Article
AS3MT, GSTO, and PNP polymorphisms: impact on arsenic methylation and implications for disease susceptibility.
Environmental research - 1 Jul 2014
Antonelli Ray, Shao Kan, Thomas David J, Sams Reeder, Cowden John
Abstract excerpt
BACKGROUND: Oral exposure to inorganic arsenic (iAs) is associated with adverse health effects. Epidemiological studies suggest differences in susceptibility to these health effects, possibly due to genotypic variation. Genetic polymorphisms in iAs metabolism could lead to increased susceptibility by altering urinary iAs metabolite concentrations. OBJECTIVE: To examine the impact of genotypic polymorphisms on iAs...
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