Population differences in the human arsenic (+3 oxidation state) methyltransferase (AS3MT) gene polymorphism detected by using genotyping method.

doi:10.1016/j.taap.2007.08.010

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Article

Population differences in the human arsenic (+3 oxidation state) methyltransferase (AS3MT) gene polymorphism detected by using genotyping method.

Toxicology and applied pharmacology - 15 Dec 2007

Fujihara Junko, Kunito Takashi, Agusa Tetsuro, Yasuda Toshihiro, Iida Reiko, Fujii Yoshimi, Takeshita Haruo

Abstract excerpt

Arsenic poisoning from drinking groundwater is a serious problem, particularly in developing Asian countries. Human arsenic (+3 oxidation state) methyltransferase (AS3MT) is known to catalyze the methylation of arsenite. Recently, a single nucleotide polymorphism (SNPs; rs17885947, M287T (T860C)) in the AS3MT gene was shown to be related to enzyme activity and considered to be related to genetic susceptibility to...

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PMID: 17889916
DOI: 10.1016/j.taap.2007.08.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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