Article
Genetic variation in glutathione S-transferase omega-1, arsenic methyltransferase and methylene-tetrahydrofolate reductase, arsenic exposure and bladder cancer: a case-control study.
Environmental health : a global access science source - 29 Jun 2012
Beebe-Dimmer Jennifer L, Iyer Priyanka T, Nriagu Jerome O, Keele Greg R, Mehta Shilpin, Meliker Jaymie R, Lange Ethan M, Schwartz Ann G, Zuhlke Kimberly A, Schottenfeld David, Cooney Kathleen A
Abstract excerpt
BACKGROUND: Ingestion of groundwater with high concentrations of inorganic arsenic has been linked to adverse health outcomes, including bladder cancer, however studies have not consistently observed any elevation in risk at lower concentrations. Genetic variability in the metabolism and clearance of arsenic is an important consideration in any investigation of its potential health risks. Therefore, we examined...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.