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Article

Additive genetic effect of APOE and BDNF on hippocampus activity.

NeuroImage - 1 Apr 2014

Kauppi Karolina, Nilsson Lars-Göran, Persson Jonas, Nyberg Lars

Abstract excerpt

Human memory is a highly heritable polygenic trait with complex inheritance patterns. To study the genetics of memory and memory-related diseases, hippocampal functioning has served as an intermediate phenotype. The importance of investigating gene-gene effects on complex phenotypes has been emphasized, but most imaging studies still focus on single polymorphisms. APOE ε4 and BDNF Met, two of the most studied...

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Source

Identifiers

PMID: 24321557
DOI: 10.1016/j.neuroimage.2013.11.049

Genes

APOE
BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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