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Article

Influence of brain-derived neurotrophic-factor and apolipoprotein E genetic variants on hippocampal volume and memory performance in healthy young adults.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Feb 2011

Richter-Schmidinger Tanja, Alexopoulos Panagiotis, Horn Marco, Maus Sebastian, Reichel Martin, Rhein Cosima, Lewczuk Piotr, Sidiropoulos Christos, Kneib Thomas, Perneczky Robert, Doerfler Arnd, Kornhuber Johannes

Abstract excerpt

Unravelling the impact of genetic variants on clinical phenotypes is a challenging task. Apolipoprotein E (ApoE) and brain-derived neurotrophic factor (BDNF) play an important role in cell growth, regeneration, synaptic plasticity, learning and memory processes. The aim of the present study was to examine the impact of BDNF Val66Met- and ApoE-polymorphisms and their interactions on hippocampal morphology and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21190051
DOI: 10.1007/s00702-010-0539-8

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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