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Article

Interaction between two cholesterol metabolism genes influences memory: findings from the Wisconsin Registry for Alzheimer's Prevention.

Journal of Alzheimer's disease : JAD - 1 Jan 2013

Engelman Corinne D, Koscik Rebecca L, Jonaitis Erin M, Okonkwo Ozioma C, Hermann Bruce P, La Rue Asenath, Sager Mark A

Abstract excerpt

The strongest genetic factor for late-onset Alzheimer's disease (AD) is APOE; nine additional susceptibility genes have recently been identified. The effect of these genes is often assumed to be additive and polygenic scores are formed as a summary measure of risk. However, interactions between these genes are likely to be important. We sought to examine the role of interactions between the nine recently...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23669301
DOI: 10.3233/JAD-130482
PMCID: PMC3759032

Genes

APOE
ABCA7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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